SUB1

Across TCGA patient cohorts, SUB1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,468 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SUB1-associated genes across cancer lineages are TENT5C, CD79A, and IGLV3-27. Each is linked with SUB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SUB1-to-partner and partner-to-SUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUB1 versus TENT5C in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUB1→partner) and Y-score (partner→SUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TENT5C →	+1.748	+0.445	<.001	<.001	3	6
HNSC	CD79A →	+1.457	+0.272	<.001	<.001	3	5
COAD	IGLV3-27 →	+1.900	+0.330	.001	.002	3	5
HNSC	IGHG1 →	+3.058	+0.357	<.001	<.001	3	5
HNSC	IGHV4-59 →	+2.999	+0.384	<.001	<.001	3	5
HNSC	IGKV1-9 →	+2.903	+0.420	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,468 associations by consensus.

SUB1 vs TENT5C — HNSC

Explore this scatter interactively →