Across TCGA patient cohorts, STYXL2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,586 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible STYXL2-associated genes across cancer lineages are MYH1, NMU, and RECK. Each is linked with STYXL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STYXL2-to-partner and partner-to-STYXL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STYXL2→partner) and Y-score (partner→STYXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYH1 →	+2.302	+1.026	<.001	<.001	3	2
PDAC	NMU →	-1.668	-0.980	.006	.006	3	2
CCRCC	RECK →	+0.470	+0.732	.009	.006	3	2
PDAC	ISLR →	+0.993	+0.905	.003	.005	3	2
CCRCC	ADCY4 →	+0.901	+0.802	<.001	.002	3	2
PDAC	EDA2R →	+0.839	+0.845	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,586 associations by consensus.

Exploration

STYXL2 survival (RNA) · tumor vs normal (RNA) · all STYXL2 data types