Across TCGA cell cohorts, STYXL2 mutation is significantly associated with the RNA expression of many other genes, with 780 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STYXL2-associated genes across cancer lineages are GSG1L2, OR1L3, and CAPZA3. Each is linked with STYXL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both STYXL2-to-partner and partner-to-STYXL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STYXL2→partner) and Y-score (partner→STYXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GSG1L2 →	+0.031	+2.552	.001	.008	3	3
BLOOD_Myeloma	OR1L3 →	+0.090	+3.491	<.001	.004	3	2
LUNG_SCLC	CAPZA3 →	+0.121	+3.232	<.001	.008	3	2
CNS	OR13C3 →	+0.049	+5.321	<.001	.005	3	2
BLOOD_Leukemia	SPINK7 →	+0.061	+3.234	<.001	.008	3	2
LARGE_INTESTINE	TNFRSF10A →	+0.957	+3.299	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 780 associations by consensus.

Exploration

STYXL2 survival (RNA) · tumor vs normal (RNA) · all STYXL2 data types