STYK1

Across TCGA cell cohorts, STYK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,709 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible STYK1-associated GO terms across cancer lineages are Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, Cellular response to topologically incorrect protein, and Positive regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with STYK1 in more than 11 cancer types. Because this analysis shows association rather than direction, both STYK1-to-partner and partner-to-STYK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway grouped by STYK1-low versus STYK1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STYK1→partner) and Y-score (partner→STYK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway →	+0.087	+1.523	<.001	<.001	3	12
STOMACH	Cellular response to topologically incorrect protein →	+0.087	+1.204	<.001	.002	3	11
BREAST	Positive regulation of tumor necrosis factor-mediated signaling pathway →	+0.131	+1.197	.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.079	+1.082	.009	.002	2	11
STOMACH	Vacuolar transport →	+0.059	+1.201	<.001	<.001	3	10
URINARY_TRACT	Response to indole-3-methanol →	+0.271	+1.753	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,709 associations by consensus.

Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway by STYK1 expression — STOMACH

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