STXBP5L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STXBP5L protein abundance is significantly associated with the protein abundance of many other proteins, with 13,418 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STXBP5L-associated proteins across cancer lineages are ZNF446_S3, RBBP6_T984, and QPCT. Each is linked with STXBP5L in more than 1 cancer types. Because this analysis shows association rather than direction, both STXBP5L-to-partner and partner-to-STXBP5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STXBP5L versus ZNF446_S3 in LSCC, with a Pearson correlation of -0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP5L→partner) and Y-score (partner→STXBP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCZNF446_S3 →-0.729-0.820<.001<.00132
LUADRBBP6_T984 →-0.876-0.892<.001<.00132
CCRCCQPCT →+1.135+0.933<.001<.00132
GBMPPM1G →-0.417-0.679<.001<.00132
GBMTMEM167B →-0.340-0.486<.001<.00132
CCRCCTUSC2 →+0.561+0.806<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,418 associations by consensus.

STXBP5L vs ZNF446_S3 — LSCC

Per-sample scatter of STXBP5L vs ZNF446_S3 in LSCC (Pearson r = -0.52).

Explore this scatter interactively →

Exploration