STXBP4

Across TCGA cell cohorts, STXBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,760 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STXBP4-associated GO terms across cancer lineages are DNA-templated DNA replication, DNA-templated transcription initiation, and DNA strand elongation. Each is linked with STXBP4 in more than 15 cancer types. Because this analysis shows association rather than direction, both STXBP4-to-partner and partner-to-STXBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by STXBP4-low versus STXBP4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP4→partner) and Y-score (partner→STXBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA-templated DNA replication →	+0.136	+0.876	.002	.002	3	16
BREAST	DNA-templated transcription initiation →	+0.065	+0.995	<.001	<.001	3	16
BONE	DNA strand elongation →	+0.156	+0.875	.001	<.001	3	16
SOFT_TISSUE	Mitotic spindle assembly →	+0.113	+1.039	<.001	<.001	3	15
LIVER	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.121	+1.134	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of cell cycle →	+0.077	+1.009	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,760 associations by consensus.

DNA-templated DNA replication by STXBP4 expression — OESOPHAGUS

Explore this box plot interactively →