STX8

Across TCGA patient cohorts, STX8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,732 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible STX8-associated proteins across cancer lineages are ANKFY1, CRK, and MYO1C. Each is linked with STX8 in more than 6 cancer types. Because this analysis shows association rather than direction, both STX8-to-partner and partner-to-STX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX8 versus ANKFY1 in LSCC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STX8→partner) and Y-score (partner→STX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANKFY1 →	+0.197	+0.345	<.001	<.001	3	7
COAD	CRK →	+0.290	+0.490	<.001	<.001	3	5
BRCA	MYO1C →	+0.379	+0.595	.002	<.001	3	4
UCEC	ARFGEF2 →	-0.316	-0.462	<.001	.003	3	4
BRCA	YWHAE →	+0.276	+0.314	<.001	<.001	3	4
LSCC	SPAG7 →	+0.266	+0.306	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,732 associations by consensus.

STX8 vs ANKFY1 — LSCC

Explore this scatter interactively →