STX8

Across TCGA cell cohorts, STX8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,520 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STX8-associated GO terms across cancer lineages are Polyamine acetylation, Spermidine acetylation, and Eosinophil activation. Each is linked with STX8 in more than 15 cancer types. Because this analysis shows association rather than direction, both STX8-to-partner and partner-to-STX8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polyamine acetylation grouped by STX8-low versus STX8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX8→partner) and Y-score (partner→STX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Polyamine acetylation →	+0.298	+0.932	<.001	.001	2	16
BONE	Spermidine acetylation →	+0.298	+0.932	<.001	.001	2	16
KIDNEY	Eosinophil activation →	+0.189	+0.834	<.001	.001	3	14
KIDNEY	Eosinophil degranulation →	+0.189	+0.834	<.001	.001	3	14
KIDNEY	Eosinophil activation involved in immune response →	+0.189	+0.834	<.001	.001	3	14
LUNG_SCLC	Cytosolic ciliogenesis →	+0.147	+0.893	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

Polyamine acetylation by STX8 expression — BONE

Explore this box plot interactively →