STX4

Across TCGA patient cohorts, STX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,553 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STX4-associated proteins across cancer lineages are PYCARD, BCKDK, and LCMT1. Each is linked with STX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both STX4-to-partner and partner-to-STX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX4 versus PYCARD in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STX4→partner) and Y-score (partner→STX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PYCARD →	+0.487	+0.310	<.001	<.001	3	5
CCRCC	BCKDK →	+0.371	+0.324	<.001	<.001	3	5
BRCA	LCMT1 →	+0.237	+0.444	.002	<.001	3	5
GBM	MVP →	+0.506	+0.318	<.001	<.001	3	5
BRCA	RABEP2 →	+0.290	+0.503	<.001	<.001	3	4
LUAD	CRYBG1 →	+0.693	+0.481	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,553 associations by consensus.

STX4 vs PYCARD — GBM

Explore this scatter interactively →