STX4

Across TCGA patient cohorts, STX4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,496 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible STX4-associated genes across cancer lineages are ASPN, COL4A2, and TMEM219. Each is linked with STX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both STX4-to-partner and partner-to-STX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX4 versus ASPN in OV, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STX4→partner) and Y-score (partner→STX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ASPN →	-1.451	-0.238	.006	.001	3	5
OV	COL4A2 →	-1.582	-0.364	<.001	<.001	3	5
OV	TMEM219 →	+0.465	+0.272	.004	<.001	3	5
OV	COL5A2 →	-1.803	-0.305	.001	<.001	3	5
OV	LINC01614 →	-1.732	-0.246	<.001	<.001	3	5
OV	AGFG2 →	+0.638	+0.211	.001	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,496 associations by consensus.

STX4 vs ASPN — OV

Explore this scatter interactively →