STX4

Across TCGA cell cohorts, STX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,160 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STX4-associated GO terms across cancer lineages are Endosomal transport, Endocytic recycling, and Golgi to plasma membrane protein transport. Each is linked with STX4 in more than 16 cancer types. Because this analysis shows association rather than direction, both STX4-to-partner and partner-to-STX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by STX4-low versus STX4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX4→partner) and Y-score (partner→STX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.059	+0.652	<.001	<.001	3	17
BLOOD_Lymphoma	Endocytic recycling →	+0.060	+0.622	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.154	+1.179	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Canonical NF-kappaB signal transduction →	+0.090	+0.772	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Viral process →	+0.079	+0.813	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Regulation of stress-activated MAPK cascade →	+0.106	+0.696	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,160 associations by consensus.

Endosomal transport by STX4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →