STX2

Across TCGA patient cohorts, STX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,121 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STX2-associated proteins across cancer lineages are ITGA5, TIMP2, and FLNA. Each is linked with STX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both STX2-to-partner and partner-to-STX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX2 versus ITGA5 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STX2→partner) and Y-score (partner→STX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGA5 →	+0.493	+0.719	.002	.004	3	8
BRCA	TIMP2 →	+0.758	+0.536	<.001	<.001	3	7
COAD	FLNA →	+0.777	+0.584	<.001	<.001	3	7
UCEC	FLNC →	+0.854	+0.677	<.001	<.001	3	7
UCEC	MAP1A →	+0.637	+0.787	<.001	<.001	3	7
COAD	PDLIM7 →	+0.672	+0.598	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,121 associations by consensus.

STX2 vs ITGA5 — OV

Explore this scatter interactively →