STX17

Across TCGA cell cohorts, STX17 RNA expression is significantly associated with the RNA expression of many other genes, with 11,912 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STX17-associated genes across cancer lineages are GPR107, ERCC6L2, and UBQLN1. Each is linked with STX17 in more than 18 cancer types. Because this analysis shows association rather than direction, both STX17-to-partner and partner-to-STX17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX17 versus GPR107 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STX17→partner) and Y-score (partner→STX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GPR107 →	+1.249	+1.266	<.001	<.001	3	19
SOFT_TISSUE	ERCC6L2 →	+1.384	+1.115	<.001	<.001	3	19
SOFT_TISSUE	UBQLN1 →	+1.089	+1.053	<.001	<.001	3	19
KIDNEY	TSTD2 →	+1.180	+1.251	<.001	<.001	3	18
STOMACH	MRTFB →	+1.428	+1.338	<.001	<.001	3	18
LUNG_NSCLC_LUSC	SECISBP2 →	+1.179	+1.191	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,912 associations by consensus.

STX17 vs GPR107 — UPPER_AERODIGESTIVE_TRACT

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