STX17

Across TCGA cell cohorts, STX17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,251 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STX17-associated GO terms across cancer lineages are Protein polyubiquitination, Nucleic acid transport, and RNA transport. Each is linked with STX17 in more than 17 cancer types. Because this analysis shows association rather than direction, both STX17-to-partner and partner-to-STX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by STX17-low versus STX17-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX17→partner) and Y-score (partner→STX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.061	+0.992	.001	.002	3	18
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.091	+0.900	.002	.007	3	16
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.091	+0.900	.002	.007	3	16
OESOPHAGUS	mRNA transport →	+0.130	+1.272	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.092	+0.883	.003	.008	3	16
PANCREAS	RNA export from nucleus →	+0.127	+0.948	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,251 associations by consensus.

Protein polyubiquitination by STX17 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →