STX17-AS1

Across TCGA pan-cancer cohorts, STX17-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated STX17-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher STX17-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated STX17-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRC show a favorable association.

MESO, KIRC, and UVM are the cancer types where STX17-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	II,III,IV	0.712	0.423	<.001	94	view →
KIRC	DFS	Median	All	0.712	0.538	<.001	76	view →
UVM	OS	Median	II,III,IV	0.821	0.435	<.001	71	view →
ACC	DFS	Median	All	0.363	0.736	.004	28	view →
SKCM	OS	Median	II,III,IV	0.648	0.809	.004	20	view →
STAD	OS	Quartile	III,IV	0.819	0.458	.004	18	view →
GBM	OS	Quartile	All	0.296	0.558	.022	18	view →
LGG	DFS	Median	All	0.656	0.848	.001	18	view →
LUAD	DFS	Median	III,IV	0.499	0.733	.007	18	view →
THYM	OS	Tertile	All	0.747	0.953	.006	14	view →
SARC	OS	Tertile	All	0.804	0.627	.029	7	view →
KIRP	DFS	Quartile	IV	0.045	0.372	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

STX17-AS1–MESO (OS)

Open the MESO breakdown →