STX12

Across TCGA patient cohorts, STX12 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,868 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STX12-associated proteins across cancer lineages are YARS2, MRPL24, and MRPL32. Each is linked with STX12 in more than 6 cancer types. Because this analysis shows association rather than direction, both STX12-to-partner and partner-to-STX12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX12 versus YARS2 in CCRCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STX12→partner) and Y-score (partner→STX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	YARS2 →	-0.380	-0.217	<.001	.008	3	7
BRCA	MRPL24 →	-0.398	-0.543	<.001	<.001	3	6
OV	MRPL32 →	-0.380	-0.512	.002	<.001	3	6
COAD	MRPL47 →	-0.412	-0.505	<.001	<.001	3	6
OV	MRPS16 →	-0.513	-0.572	<.001	<.001	3	6
COAD	MRPS22 →	-0.465	-0.543	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,868 associations by consensus.

STX12 vs YARS2 — CCRCC

Explore this scatter interactively →