STX12

Across TCGA cell cohorts, STX12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,801 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible STX12-associated GO terms across cancer lineages are Macroautophagy, Endocytic recycling, and Vesicle budding from membrane. Each is linked with STX12 in more than 15 cancer types. Because this analysis shows association rather than direction, both STX12-to-partner and partner-to-STX12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by STX12-low versus STX12-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX12→partner) and Y-score (partner→STX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.059	+0.714	.002	<.001	3	16
STOMACH	Endocytic recycling →	+0.061	+0.708	.001	.001	3	16
SOFT_TISSUE	Vesicle budding from membrane →	+0.075	+0.801	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.054	+0.765	.002	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.054	+0.765	.002	<.001	3	14
LARGE_INTESTINE	Regulation of ER to Golgi vesicle-mediated transport →	+0.110	+0.734	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,801 associations by consensus.

Macroautophagy by STX12 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →