STX11

Across TCGA cell cohorts, STX11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,024 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STX11-associated GO terms across cancer lineages are Regulation of late endosome to lysosome transport, Regulation of vacuolar transport, and Cytotoxic T cell degranulation. Each is linked with STX11 in more than 17 cancer types. Because this analysis shows association rather than direction, both STX11-to-partner and partner-to-STX11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of late endosome to lysosome transport grouped by STX11-low versus STX11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX11→partner) and Y-score (partner→STX11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of late endosome to lysosome transport →	-0.246	-1.691	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Regulation of vacuolar transport →	-0.246	-1.691	<.001	<.001	3	18
BONE	Cytotoxic T cell degranulation →	-0.355	-1.223	<.001	<.001	3	12
STOMACH	Receptor localization to synapse →	-0.156	-0.851	<.001	<.001	3	11
BREAST	Negative regulation of post-translational protein modification →	+0.081	+0.585	<.001	.001	3	11
BONE	Negative regulation of p38MAPK cascade →	+0.270	+1.146	<.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,024 associations by consensus.

Regulation of late endosome to lysosome transport by STX11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →