STX10

Across TCGA patient cohorts, STX10 protein abundance is significantly associated with the RNA expression of many other genes, with 10,089 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STX10-associated genes across cancer lineages are MRPL4, DNASE2, and PPP1R16B. Each is linked with STX10 in more than 2 cancer types. Because this analysis shows association rather than direction, both STX10-to-partner and partner-to-STX10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX10 versus MRPL4 in BRCA, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STX10→partner) and Y-score (partner→STX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPL4 →	+0.578	+0.314	.001	<.001	3	3
BRCA	DNASE2 →	+0.447	+0.261	<.001	.001	3	3
CCRCC	PPP1R16B →	-0.602	-0.214	.001	.001	3	2
BRCA	KXD1 →	+0.439	+0.263	<.001	.001	3	2
BRCA	TARS1 →	+0.484	+0.289	<.001	.001	3	2
LUAD	HOXD9 →	-0.567	-0.182	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,089 associations by consensus.

STX10 vs MRPL4 — BRCA

Explore this scatter interactively →