STS

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STS protein abundance is significantly associated with the RNA expression of many other genes, with 12,234 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STS-associated genes across cancer lineages are RNU2-17P, RAB5IF, and MRGBP. Each is linked with STS in more than 1 cancer types. Because this analysis shows association rather than direction, both STS-to-partner and partner-to-STS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STS versus RNU2-17P in OV, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STS→partner) and Y-score (partner→STS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRNU2-17P →-0.822-0.876.006.00532
OVRAB5IF →-1.519-0.917.007.00231
OVMRGBP →-0.824-0.865.004.00431
OVGMEB2 →-0.996-0.941<.001.00131
OVWFS1 →-1.055-0.873.002.00431
OVSLC2A4RG →-0.993-0.943<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,234 associations by consensus.

STS vs RNU2-17P — OV

Per-sample scatter of STS vs RNU2-17P in OV (Pearson r = -0.51).

Explore this scatter interactively →

Exploration