STRN4

Across TCGA cell cohorts, STRN4 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STRN4-associated genes across cancer lineages are OR10K1, ELOA3DP, and PRKACG. Each is linked with STRN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRN4-to-partner and partner-to-STRN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K1 grouped by STRN4-low versus STRN4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRN4→partner) and Y-score (partner→STRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR10K1 →	+0.006	+5.977	<.001	.001	3	2
BLOOD_Leukemia	ELOA3DP →	+0.096	+3.007	.004	.007	3	2
URINARY_TRACT	PRKACG →	+0.005	+4.087	<.001	.009	3	1
SOFT_TISSUE	SPRR3 →	+0.061	+4.930	<.001	.008	3	1
SOFT_TISSUE	TEX55 →	+0.026	+5.369	<.001	.004	3	1
SOFT_TISSUE	GP9 →	+0.026	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR10K1 by STRN4 expression — SOFT_TISSUE

Explore this box plot interactively →