Across TCGA pan-cancer cohorts, STRN3 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated STRN3 data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher STRN3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated STRN3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

PRAD, ESCA, and UCEC are the cancer types where STRN3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PRAD	DFS	Median	All	0.113	0.935	<.001	6	view →
ESCA	OS	Median	All	0.295	0.704	.013	6	view →
UCEC	DFS	Median	All	0.971	0.892	.045	4	view →
BLCA	DFS	Median	IV	1.000	0.199	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: STRN3 tumor-vs-normal RNA expression · all STRN3 data types