Across TCGA patient cohorts, STRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,127 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible STRN3-associated genes across cancer lineages are AP4S1, RAB2B, and DTD2. Each is linked with STRN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both STRN3-to-partner and partner-to-STRN3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRN3→partner) and Y-score (partner→STRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AP4S1 →	+0.500	+0.235	<.001	<.001	3	8
BRCA	RAB2B →	+0.431	+0.206	<.001	<.001	3	8
HNSC	DTD2 →	+0.780	+0.267	<.001	.003	3	8
COAD	NEDD8 →	+0.615	+0.249	<.001	<.001	3	8
BRCA	FAM177A1 →	+0.760	+0.326	<.001	<.001	3	8
HNSC	HECTD1 →	+0.761	+0.377	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,127 associations by consensus.

Exploration

STRN3 survival (RNA) · tumor vs normal (RNA) · all STRN3 data types