Across TCGA patient cohorts, STRN3 mutation is significantly associated with the RNA expression of many other genes, with 2,901 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRN3-associated genes across cancer lineages are LINC02399, LINC02616, and SCG2. Each is linked with STRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRN3-to-partner and partner-to-STRN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRN3→partner) and Y-score (partner→STRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02399 →	+0.223	+3.882	<.001	.004	3	2
BLCA	LINC02616 →	+1.005	+3.599	<.001	.009	3	2
UCEC	SCG2 →	+0.694	+1.737	<.001	.002	3	2
UCEC	CACNG5 →	+0.731	+1.643	<.001	.003	3	2
CESC	OR2P1P →	+0.080	+4.669	<.001	<.001	3	2
CESC	MIR613 →	+0.484	+3.567	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

Exploration

STRN3 survival (RNA) · tumor vs normal (RNA) · all STRN3 data types