STRN

Across TCGA pan-cancer cohorts, STRN mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated STRN data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher STRN mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated STRN expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where STRN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.883	.023	48	view →
PDAC	OS	Tertile	All	0.582	0.422	.004	26	view →
CCRCC	OS	Quartile	All	0.917	0.685	.012	26	view →
HNSC	DFS	Quartile	III,IV	0.946	0.678	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

STRN–COAD (DFS)

Open the COAD breakdown →