STRN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STRN RNA expression is significantly associated with the protein abundance of many other proteins, with 19,335 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STRN-associated proteins across cancer lineages are HLA-DMA, PSMB10, and PSME2. Each is linked with STRN in more than 4 cancer types. Because this analysis shows association rather than direction, both STRN-to-partner and partner-to-STRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRN versus HLA-DMA in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STRN→partner) and Y-score (partner→STRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHLA-DMA →-0.746-0.328<.001<.00135
GBMPSMB10 →-0.371-0.279<.001<.00134
HNSCPSME2 →-0.450-0.529<.001.00134
HNSCHNRNPLL →+0.227+0.484<.001.00234
HNSCBIN2_S444 →-0.805-0.478<.001.00334
LSCCCAMSAP2 →+0.295+0.423<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,335 associations by consensus.

STRN vs HLA-DMA — GBM

Per-sample scatter of STRN vs HLA-DMA in GBM (Pearson r = -0.30).

Explore this scatter interactively →

Exploration