STRN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STRN protein abundance is significantly associated with the protein abundance of many other proteins, with 18,094 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible STRN-associated proteins across cancer lineages are STRN_S137, STRN_S245, and YWHAQ. Each is linked with STRN in more than 8 cancer types. Because this analysis shows association rather than direction, both STRN-to-partner and partner-to-STRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRN versus STRN_S137 in PDAC, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STRN→partner) and Y-score (partner→STRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACSTRN_S137 →+0.596+0.188<.001<.00129
LSCCSTRN_S245 →+0.439+0.166<.001<.00138
HNSCYWHAQ →+0.403+0.241<.001<.00136
HNSCSTAMBP →+0.248+0.196<.001<.00136
BRCATCP1 →+0.298+0.252<.001<.00135
HNSCMEMO1 →+0.314+0.178<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,094 associations by consensus.

STRN vs STRN_S137 — PDAC

Per-sample scatter of STRN vs STRN_S137 in PDAC (Pearson r = 0.46).

Explore this scatter interactively →

Exploration