STRIP2

Across TCGA pan-cancer cohorts, STRIP2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated STRIP2 data layer compared with 28 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher STRIP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated STRIP2 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where STRIP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.449	0.857	.002	13	view →
PDAC	DFS	Quartile	All	0.173	0.610	.023	10	view →
LSCC	DFS	Quartile	All	0.909	0.588	.010	7	view →
GBM	DFS	Tertile	All	0.416	0.252	.033	6	view →
CCRCC	DFS	Tertile	III,IV	0.123	0.856	.036	3	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

STRIP2–LUAD (OS)

Open the LUAD breakdown →