STRIP2

Across TCGA patient cohorts, STRIP2 mutation is significantly associated with the RNA expression of many other genes, with 3,505 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRIP2-associated genes across cancer lineages are BUB3, UHRF1, and MRPL39. Each is linked with STRIP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both STRIP2-to-partner and partner-to-STRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BUB3 grouped by STRIP2-low versus STRIP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRIP2→partner) and Y-score (partner→STRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BUB3 →	+0.524	+3.348	<.001	.005	3	3
UCEC	UHRF1 →	+1.115	+3.765	<.001	<.001	3	3
UCEC	MRPL39 →	+0.452	+2.273	<.001	<.001	3	3
UCEC	CCNB2 →	+0.819	+3.115	<.001	<.001	3	3
UCEC	TIMM22 →	+0.431	+1.992	<.001	<.001	2	4
UCEC	ATG16L1 →	+0.277	+2.263	.009	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,505 associations by consensus.

BUB3 by STRIP2 expression — COAD

Explore this box plot interactively →