STRBP

Across TCGA pan-cancer cohorts, STRBP mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated STRBP data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher STRBP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated STRBP expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where STRBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.892	.028	42	view →
PDAC	OS	Median	III,IV	0.608	0.283	.006	33	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.812	.024	12	view →
CCRCC	DFS	Median	All	0.831	0.635	.005	9	view →
LSCC	DFS	Tertile	II,III,IV	0.939	0.579	.013	8	view →
GBM	OS	Quartile	All	0.592	0.339	.005	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

STRBP–COAD (DFS)

Open the COAD breakdown →