STRA6

Across TCGA pan-cancer cohorts, STRA6 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated STRA6 data layer compared with 20 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher STRA6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated STRA6 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where STRA6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	1.000	0.875	.004	44	view →
UCEC	DFS	Tertile	III,IV	0.483	1.000	.025	8	view →
LUAD	OS	Median	III,IV	0.536	0.976	.016	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

STRA6–CCRCC (OS)

Open the CCRCC breakdown →