STPG4

Across TCGA patient cohorts, STPG4 mutation is significantly associated with the RNA expression of many other genes, with 713 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STPG4-associated genes across cancer lineages are LINC02071, GLULP6, and CFHR2. Each is linked with STPG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG4-to-partner and partner-to-STPG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02071 grouped by STPG4-low versus STPG4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG4→partner) and Y-score (partner→STPG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02071 →	+0.130	+2.377	.001	.007	3	2
SKCM	GLULP6 →	+0.058	+5.097	<.001	.008	3	2
HNSC	CFHR2 →	+0.049	+7.954	<.001	.008	3	1
UCEC	CCR8 →	+0.539	+3.375	.002	.005	3	1
UCEC	TIGD2 →	+0.896	+3.364	<.001	.005	3	1
UCEC	ZNF559 →	+0.540	+3.343	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 713 associations by consensus.

LINC02071 by STPG4 expression — UCEC

Explore this box plot interactively →