STPG4

Across TCGA patient cohorts, STPG4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STPG4-associated genes across cancer lineages are Monocytes, Epithelial cells, and Keratinocytes. Each is linked with STPG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG4-to-partner and partner-to-STPG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by STPG4-low versus STPG4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG4→partner) and Y-score (partner→STPG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Monocytes →	+0.048	+5.734	<.001	.027	3	1
UCEC	Epithelial cells →	-0.126	-3.161	<.001	.019	3	1
UCEC	Keratinocytes →	-0.017	-3.193	.017	.011	3	1
UCEC	Sebocytes →	-0.038	-2.967	.003	.036	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Monocytes by STPG4 expression — COAD

Explore this box plot interactively →