Across TCGA patient cohorts, STPG3 mutation is significantly associated with the RNA expression of many other genes, with 1,580 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STPG3-associated genes across cancer lineages are MIR5691, RNU6-210P, and PLS3-AS1. Each is linked with STPG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG3-to-partner and partner-to-STPG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG3→partner) and Y-score (partner→STPG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5691 →	+0.247	+3.109	.004	.007	3	2
BRCA	RNU6-210P →	+0.443	+8.471	<.001	.005	3	1
UCEC	PLS3-AS1 →	+0.394	+3.263	<.001	.008	3	1
UCEC	MIR7702 →	+0.309	+4.738	<.001	.002	3	1
UCEC	ZNF280B →	+0.846	+3.470	<.001	.003	3	1
UCEC	MIR6500 →	+0.337	+3.133	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,580 associations by consensus.

Exploration

STPG3 survival (RNA) · tumor vs normal (RNA) · all STPG3 data types