Across TCGA patient cohorts, STPG3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STPG3-associated genes across cancer lineages are Neutrophils, Monocytes, and Epithelial cells. Each is linked with STPG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG3-to-partner and partner-to-STPG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG3→partner) and Y-score (partner→STPG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Neutrophils →	+0.028	+3.200	.001	.047	3	2
COAD	Monocytes →	+0.028	+4.734	<.001	.045	3	1
UCEC	Epithelial cells →	-0.092	-2.313	.010	.035	3	1
UCEC	Th2 cells →	+0.241	+2.321	.007	.036	3	1
UCEC	iDC →	-0.180	-3.459	.031	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

STPG3 survival (RNA) · tumor vs normal (RNA) · all STPG3 data types