STPG3-AS1

Across TCGA pan-cancer cohorts, STPG3-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated STPG3-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher STPG3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated STPG3-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

PAAD, ACC, and HNSC are the cancer types where STPG3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	All	0.429	0.176	<.001	49	view →
ACC	OS	Median	III,IV	0.314	0.792	.003	40	view →
HNSC	OS	Quartile	II,III,IV	0.810	0.656	.003	39	view →
KIRC	DFS	Quartile	II,III,IV	0.360	0.643	.006	33	view →
COAD	OS	Quartile	All	0.727	0.864	.008	18	view →
PRAD	DFS	Tertile	All	0.812	0.927	<.001	18	view →
BLCA	OS	Median	II,III,IV	0.768	0.664	.016	14	view →
UCS	DFS	Median	All	0.405	0.622	.029	12	view →
LUAD	OS	Tertile	II,III,IV	0.798	0.651	.019	10	view →
DLBC	OS	Tertile	All	0.732	1.000	.015	8	view →
MESO	OS	Tertile	All	0.493	0.279	.019	6	view →
ESCA	OS	Median	III,IV	0.633	0.319	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

STPG3-AS1–PAAD (DFS)

Open the PAAD breakdown →