STOX2

Across TCGA cell cohorts, STOX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,352 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible STOX2-associated GO terms across cancer lineages are Cytoplasmic translation, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, and mRNA splicing, via spliceosome. Each is linked with STOX2 in more than 13 cancer types. Because this analysis shows association rather than direction, both STOX2-to-partner and partner-to-STOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by STOX2-low versus STOX2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STOX2→partner) and Y-score (partner→STOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cytoplasmic translation →	+0.132	+1.250	<.001	<.001	3	14
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.090	+1.192	<.001	<.001	3	12
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.090	+1.192	<.001	<.001	3	12
STOMACH	Epigenetic regulation of gene expression →	+0.072	+1.592	<.001	.001	3	12
OESOPHAGUS	Nucleic acid transport →	+0.134	+1.470	<.001	<.001	3	12
OESOPHAGUS	RNA transport →	+0.134	+1.470	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,352 associations by consensus.

Cytoplasmic translation by STOX2 expression — OESOPHAGUS

Explore this box plot interactively →