STOX1

Across TCGA cell cohorts, STOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,149 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STOX1-associated GO terms across cancer lineages are Positive regulation of cyclin-dependent protein kinase activity, Cellular response to nitrosative stress, and Regulation of double-strand break repair via homologous recombination. Each is linked with STOX1 in more than 17 cancer types. Because this analysis shows association rather than direction, both STOX1-to-partner and partner-to-STOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cyclin-dependent protein kinase activity grouped by STOX1-low versus STOX1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STOX1→partner) and Y-score (partner→STOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of cyclin-dependent protein kinase activity →	-0.203	-1.143	<.001	<.001	3	18
STOMACH	Cellular response to nitrosative stress →	-0.226	-1.086	<.001	<.001	3	14
BONE	Regulation of double-strand break repair via homologous recombination →	+0.080	+0.747	<.001	<.001	3	13
LIVER	Positive regulation of DNA repair →	+0.074	+0.988	<.001	.005	3	13
BONE	Regulation of body fluid levels →	-0.106	-1.201	<.001	<.001	3	12
BONE	DNA strand elongation involved in DNA replication →	+0.229	+1.345	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,149 associations by consensus.

Positive regulation of cyclin-dependent protein kinase activity by STOX1 expression — BLOOD_Myeloma

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