STON2

Across TCGA patient cohorts, STON2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,267 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STON2-associated proteins across cancer lineages are STON2_S227, CASP4, and CEP170B. Each is linked with STON2 in more than 5 cancer types. Because this analysis shows association rather than direction, both STON2-to-partner and partner-to-STON2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STON2 versus STON2_S227 in CCRCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STON2→partner) and Y-score (partner→STON2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	STON2_S227 →	+0.809	+1.633	<.001	<.001	3	6
GBM	CASP4 →	-0.472	-0.801	.002	.003	3	5
HNSC	CEP170B →	+0.336	+0.992	<.001	<.001	3	5
GBM	DOK1 →	-0.296	-0.840	<.001	<.001	3	5
UCEC	S100A2 →	+1.577	+0.629	.001	.002	3	5
HNSC	SEC23B →	-0.363	-0.932	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,267 associations by consensus.

STON2 vs STON2_S227 — CCRCC

Explore this scatter interactively →