STON2

Across TCGA patient cohorts, STON2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,692 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STON2-associated genes across cancer lineages are UNGP3, ZC3H14, and FRMD6-AS1. Each is linked with STON2 in more than 8 cancer types. Because this analysis shows association rather than direction, both STON2-to-partner and partner-to-STON2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STON2 versus UNGP3 in CCRCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STON2→partner) and Y-score (partner→STON2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	UNGP3 →	+1.219	+0.647	<.001	<.001	3	9
BRCA	ZC3H14 →	+0.515	+0.460	<.001	<.001	3	5
LSCC	FRMD6-AS1 →	+0.783	+0.464	<.001	<.001	3	5
CCRCC	RNF152 →	+1.643	+0.546	<.001	<.001	3	4
HNSC	DAAM1 →	+0.787	+0.822	.002	<.001	3	4
LSCC	KCNMB1 →	-0.518	-0.503	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,692 associations by consensus.

STON2 vs UNGP3 — CCRCC

Explore this scatter interactively →