STON2

Across TCGA cell cohorts, STON2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,876 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STON2-associated GO terms across cancer lineages are Substantia nigra development, Cytoplasmic translation, and Calcium ion transmembrane transport. Each is linked with STON2 in more than 10 cancer types. Because this analysis shows association rather than direction, both STON2-to-partner and partner-to-STON2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substantia nigra development grouped by STON2-low versus STON2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STON2→partner) and Y-score (partner→STON2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Substantia nigra development →	+0.089	+1.293	.001	.003	3	11
STOMACH	Cytoplasmic translation →	+0.079	+1.627	.002	.002	3	11
LIVER	Calcium ion transmembrane transport →	-0.051	-1.569	.005	.002	3	11
PANCREAS	Membrane hyperpolarization →	-1.113	-1.377	.001	.003	3	10
STOMACH	Regulation of myoblast fusion →	+0.142	+2.349	<.001	<.001	3	10
KIDNEY	Negative regulation of inflammatory response to wounding →	+0.190	+1.315	.004	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,876 associations by consensus.

Substantia nigra development by STON2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →