STOML2

Across TCGA cell cohorts, STOML2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,602 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible STOML2-associated GO terms across cancer lineages are tRNA export from nucleus, Maturation of 5.8S rRNA, and Nucleoside monophosphate biosynthetic process. Each is linked with STOML2 in more than 17 cancer types. Because this analysis shows association rather than direction, both STOML2-to-partner and partner-to-STOML2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA export from nucleus grouped by STOML2-low versus STOML2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STOML2→partner) and Y-score (partner→STOML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	tRNA export from nucleus →	+0.166	+1.190	<.001	.001	2	18
BONE	Maturation of 5.8S rRNA →	+0.132	+0.761	.007	<.001	3	16
PANCREAS	Nucleoside monophosphate biosynthetic process →	+0.123	+0.744	<.001	<.001	3	15
BONE	U4 snRNA 3'-end processing →	+0.203	+0.747	<.001	<.001	3	14
BONE	rRNA metabolic process →	+0.131	+0.648	.001	.003	3	14
BONE	Ribosomal small subunit biogenesis →	+0.129	+0.647	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,602 associations by consensus.

tRNA export from nucleus by STOML2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →