STOML1

Across TCGA pan-cancer cohorts, STOML1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated STOML1 data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher STOML1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STOML1 expression acts as an unfavorable survival marker.

LSCC, LUAD, and HNSC are the cancer types where STOML1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.485	1.000	.013	11	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
HNSC	DFS	Median	IV	0.666	0.962	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

STOML1–LSCC (DFS)

Open the LSCC breakdown →