STOML1

Across TCGA patient cohorts, STOML1 mutation is significantly associated with the RNA expression of many other genes, with 797 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STOML1-associated genes across cancer lineages are RPL7L1P4, RNU6-1290P, and RNU6-633P. Each is linked with STOML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STOML1-to-partner and partner-to-STOML1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL7L1P4 grouped by STOML1-low versus STOML1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STOML1→partner) and Y-score (partner→STOML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL7L1P4 →	+0.063	+4.953	.002	.002	3	2
BLCA	RNU6-1290P →	+0.436	+6.444	<.001	.001	3	2
COAD	RNU6-633P →	+1.162	+5.374	<.001	.001	3	2
UCEC	RNU6-280P →	+0.260	+4.022	<.001	<.001	3	2
UCEC	RNA5SP396 →	+0.576	+2.784	<.001	.004	3	2
UCEC	MIR548H3 →	+0.263	+2.599	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 797 associations by consensus.

RPL7L1P4 by STOML1 expression — SKCM

Explore this box plot interactively →