STOML1

Across TCGA cell cohorts, STOML1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STOML1-associated genes across cancer lineages are FABP12, RBMY1B, and SPHKAP. Each is linked with STOML1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STOML1-to-partner and partner-to-STOML1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP12 grouped by STOML1-low versus STOML1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STOML1→partner) and Y-score (partner→STOML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FABP12 →	+0.189	+4.981	<.001	.008	3	1
SKIN	RBMY1B →	+1.113	+4.977	<.001	.007	3	1
BLOOD_Leukemia	SPHKAP →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	HIGD1C →	+0.108	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FABP12 by STOML1 expression — CNS

Explore this box plot interactively →