STOM

Across TCGA pan-cancer cohorts, STOM mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated STOM data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher STOM mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STOM expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

COAD, UCEC, and PDAC are the cancer types where STOM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.885	1.000	.019	36	view →
UCEC	DFS	Tertile	All	0.749	0.976	.006	26	view →
PDAC	OS	Median	All	0.702	0.930	.001	11	view →
HNSC	DFS	Tertile	All	0.786	0.574	.027	8	view →
LUAD	OS	Median	III,IV	0.231	0.624	.019	6	view →
CCRCC	OS	Median	All	0.907	0.768	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

STOM–COAD (DFS)

Open the COAD breakdown →