STOM

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STOM protein abundance is significantly associated with the RNA expression of many other genes, with 15,037 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STOM-associated genes across cancer lineages are CXCR2, S100A12, and BCL2A1. Each is linked with STOM in more than 7 cancer types. Because this analysis shows association rather than direction, both STOM-to-partner and partner-to-STOM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STOM versus CXCR2 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STOM→partner) and Y-score (partner→STOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCXCR2 →+1.063+0.436<.001.00338
HNSCS100A12 →+1.980+0.331<.001<.00137
GBMBCL2A1 →+1.165+0.499<.001<.00136
LSCCFCGR3B →+1.186+0.453<.001<.00136
LSCCCXCR1 →+1.023+0.514<.001<.00136
UCECMIR223HG →+1.033+0.436<.001.00827
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,037 associations by consensus.

STOM vs CXCR2 — UCEC

Per-sample scatter of STOM vs CXCR2 in UCEC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration