STOM

Across TCGA cell cohorts, STOM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,634 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STOM-associated GO terms across cancer lineages are Host-mediated activation of viral genome replication, Positive regulation of protein targeting to membrane, and Host-mediated perturbation of viral genome replication. Each is linked with STOM in more than 10 cancer types. Because this analysis shows association rather than direction, both STOM-to-partner and partner-to-STOM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Host-mediated activation of viral genome replication grouped by STOM-low versus STOM-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STOM→partner) and Y-score (partner→STOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Host-mediated activation of viral genome replication →	+0.114	+2.041	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of protein targeting to membrane →	+0.168	+2.252	<.001	<.001	3	10
KIDNEY	Host-mediated perturbation of viral genome replication →	+0.161	+2.192	<.001	<.001	3	9
SOFT_TISSUE	Regulation of protein targeting →	+0.132	+2.362	<.001	<.001	3	8
SOFT_TISSUE	Regulation of protein targeting to membrane →	+0.132	+2.362	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Glycolipid catabolic process →	+0.189	+2.314	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,634 associations by consensus.

Host-mediated activation of viral genome replication by STOM expression — SOFT_TISSUE

Explore this box plot interactively →