STMP1

Across TCGA pan-cancer cohorts, STMP1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of STMP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where STMP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STMP1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LUAD, THCA, and HNSC are the cancer types where STMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.667	<.001	11	view →
THCA	Male	III,IV	−0.877	<.001	10	view →
HNSC	All	IV	+0.491	.004	10	view →
LUSC	Female	All	+1.210	<.001	8	view →
LIHC	Male	II,III,IV	+0.939	<.001	8	view →
UCEC	All	II,III,IV	+0.750	<.001	8	view →
KIRC	All	II,III,IV	−0.415	<.001	8	view →
KICH	Female	All	−1.002	<.001	7	view →
BLCA	All	All	+0.655	<.001	7	view →
BRCA	All	II,III,IV	+0.597	<.001	6	view →
STAD	Female	All	+0.687	.020	4	view →
CHOL	Male	All	+1.814	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

STMP1–LUAD

Open the LUAD breakdown →