STMND1

Across TCGA cell cohorts, STMND1 mutation is significantly associated with the mutation status of many other genes, with 390 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STMND1-associated genes across cancer lineages are HNRNPH3, ASCL5, and GABARAPL3. Each is linked with STMND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STMND1-to-partner and partner-to-STMND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPH3 grouped by STMND1-low versus STMND1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STMND1→partner) and Y-score (partner→STMND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HNRNPH3 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	ASCL5 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	GABARAPL3 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	KRTAP9-2 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	ISY1 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	KRTAP4-16 →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

HNRNPH3 by STMND1 expression — LARGE_INTESTINE

Explore this box plot interactively →